Immunophenotypic analysis on circulating T cells for early diagnosis of lung cancer.

The immune system continuously interacts with tumors, possibly leading to systemic alterations in circulating immune cells. However, the potential of these cancer-associated changes for diagnostic purposes remains poorly explored. To investigate this, we conducted a comprehensive flow cytometric analysis of 452 peripheral blood mononuclear cell (PBMC) samples from 206 non-small-cell lung cancer (NSCLC) patients, 100 small-cell lung cancer (SCLC) patients, 94 healthy individuals, and 52 benign lung disease (BLD) patients.

Hallux valgus interphalangeus is more common in juvenile-onset hallux valgus than in adult-onset hallux valgus.

Background: This study aimed to compare the prevalence of hallux valgus interphalangeus (HVI) in juvenile-onset hallux valgus and adult-onset hallux valgus and to analyze the correlation between the hallux interphalangeal angle (HIA) and other radiographic parameters in juvenile-onset hallux valgus.

Methods: This retrospective study included 640 feet and 320 patients with hallux valgus (160 juvenile-onset and 160 adult-onset cases). Eight radiographic parameters were measured: HIA, hallux valgus angle, intermetatarsal angle, talonavicular coverage angle, anteroposterior talocalcaneal angle, lateral talocalcaneal angle, lateral talo-first metatarsal angle, and calcaneal pitch.

Effect of individualized versus conventional perioperative blood pressure management on postoperative major complications in high-risk patients undergoing noncardiac surgery: study protocol for the SPROUT-4 multicenter randomized controlled trial.

Background: Intraoperative hypotension is very common during surgery and is linked to major organ dysfunction and mortality. Current perioperative blood pressure management is largely based on universal blood pressure thresholds ranging from a mean arterial pressure of 60-70 mmHg. However, the effectiveness of this conventional management remains unproven in prospective randomized trials.

Correlation between individual thigh muscle volume and grip strength in relation to sarcopenia with automated muscle segmentation.

Introduction: Grip strength serves as a significant marker for diagnosing and assessing sarcopenia, particularly in elderly populations. The study aims to explore the relationship between individual thigh muscle volumes and grip strength, leveraging advanced AI-based UNETR segmentation techniques for accurate muscle volume assessment.

Methods: The study included 49 participants from a cohort of 478 patients diagnosed with hip fractures at Gyeongsang National University Hospital.

Relationship Between Electronegativity of the Extra-Framework Cations and Adsorption Capacity for CO Gas on Mordenite Framework.

Synthetic mordenite is widely used as a molecular sieve, adsorbent, and catalyst. To enhance these functionalities, it is crucial to understand the ion-exchange properties and cation-exchange sites of the zeolite. In this study, we analyzed the structural changes in fully Cs-, Sr-, Cd-, and Pb-exchanged mordenite by using synchrotron X-ray powder diffraction under ambient conditions.