Brassinosteroids Affect the Symbiosis Between the AM Fungus and Solanaceous Host Plants.

Together with several proteins involved in brassinosteroid (BR) signaling and synthesis, the membrane steroid binding protein 1 (MSBP1) was identified within the interactome of the sucrose transporter of tomato (SlSUT2). We asked whether MSBP1 is also involved in BR signaling as assumed for the AtMSBP1 protein from Arabidopsis and whether it impacts root colonization with arbuscular mycorrhizal (AM) fungi in a similar way as shown previously for SlSUT2. In addition, we asked whether brassinosteroids affect efficiency of root colonization by AM fungi.

Canavan disease: neuromorphological and biochemical analysis of a brain biopsy specimen.

In this study we present a patient with Canavan disease or Van Bogaert and Bertrand type of spongiform leukodystrophy, proven by brain biopsy. We performed morphological studies and biochemical assays on fresh homogenates of the grey and white matter. Quantitative neuromorphological analysis of the cortex showed normal values except for poor dendritic arborization of the inner layers.

Morphological and biochemical analysis of a brain biopsy in a case of idiopathic Lennox-Gastaut syndrome.

The results of a qualitative and quantitative neuromorphological and a biochemical analysis of a brain biopsy from a 7-year-old boy with an idiopathic type of Lennox-Gastaut syndrome (LGS) are reported. A disturbance in cerebral energy metabolism as expressed by the pyruvate pathway could be ruled out. Degenerative or ischemic lesions were not found.

Anomalies of the cerebral cortex in a case of epilepsia partialis continua.

Morphological and biochemical findings are described from the brain biopsy of an 11-year-old girl with intractable type II epilepsia partialis continua. Computerized tomography scan showed severe progressive central and cortical atrophy, mainly of the right hemisphere. Brain biopsy revealed microangiopathy of the cortex-penetrating arteries, patchy necrosis of the cortex, and small loose infiltrates of lymphocytic cells.