Phosphate supplementation in young men: lack of effect on calcium homeostasis and bone turnover.

Objective: To examine the effect of phosphate supplements on calcium homeostasis and bone turnover in young men.

Design: Study 1 was a randomised, controlled, cross-over trial of 1000 mg elemental phosphate given for one week, with a standard diet of 800 mg/d each of calcium and phosphorus. Study 2 was an escalating dose study of 0, 1000, 1500 and 2000 mg/d elemental phosphate, each given for one week, with a standard diet of 1000 mg/d each of calcium and phosphate.

Appropriate public health responses to clusters: the art of being responsibly responsive.

Between 1981 and 1988, the Minnesota Department of Health actively responded to over 400 reports from persons concerned about disease occurrence in their community, school, or workplace. Almost all of these reports involved perceived excesses of cases of cancer. Although there is little potential for identifying unsuspected public health problems or developing new etiologic insights, the Minnesota Department of Health has found that responding to reported clusters is a legitimate and necessary public health activity.

Prevalence of hypertension and associated risk factors among diabetic individuals. The Three-City Study.

A cross-sectional study was conducted from 1979 through 1982 in three rural Minnesota cities to describe the natural history of diabetes mellitus. Detailed abstracts of the medical records of physician-defined diabetic individuals were used to construct medical profiles. As part of the effort, the date of physician-defined hypertension was identified and used to calculate hypertension prevalence.

Feasibility study of a statewide pathology-based cancer surveillance system in Minnesota. I. Information characteristics.

The Minnesota Department of Health has completed a 2-year feasibility study comparing the completeness and accuracy of information from pathology-based cancer ascertainment with that of the traditional surveillance method based on hospital discharge records. Overall, for incident cancers, the primary site designation of the pathology-based system was correct for 94.5% of the cancers, and the histologic designation was correct for 97.