Publications by authors named "H J van Lingen"

Article Synopsis
  • - Normalization of gene expression data is crucial for analyzing RNA-sequencing data, particularly in differential expression studies, but its effects on multivariate analysis, like PCA, are less understood.
  • - This study examines twelve normalization methods on both simulated and real data to see how they influence PCA outcomes, including sample clustering and gene ranking.
  • - Results show that while PCA score plots might look similar across different normalization techniques, the biological insights drawn from these models can vary significantly based on the normalization choice.
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Estimating daily enteric hydrogen (H) and methane (CH) emitted from dairy cattle using spot sampling techniques requires accurate sampling schemes. These sampling schemes determine the number of daily samplings and their intervals. This simulation study assessed the accuracy of daily H and CH emissions from dairy cattle using various sampling schemes for gas collection.

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Methionine (Met) is the first limiting amino acid in corn and soybean meal-based diets (containing L-Met) in broiler chickens, which are often supplemented with synthetic DL-Met or DL-Hydroxy Met (OH-Met). Our objective was to quantitatively assess the efficacy of synthetic Met sources and determine differences in growth rate of broilers fed at or below requirements in response to Met intake. A systematic literature search resulted in building a database containing 480 treatment means from 39 articles published between 1985 and 2019 globally.

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3-Nitrooxypropanol (3-NOP) supplementation to cattle diets mitigates enteric CH emissions and may also be economically beneficial at farm level. However, the wider rumen metabolic response to methanogenic inhibition by 3-NOP and the intermediary metabolite requires further exploration. Furthermore, supplementation potently decreases CH emissions from cattle.

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