Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy.

As an animal matures, its neural circuit undergoes alterations, yet the developmental changes in intracellular organelles to facilitate these changes is less understood. Using 3D electron microscopy and deep learning, the study develops semi-automated methods for reconstructing mitochondria in C. elegans and collected mitochondria reconstructions from normal reproductive stages and dauer, enabling comparative study on mitochondria structure within the neuromuscular system.

Need of Treatment Modification During Entecavir Therapy in Patients with Chronic Hepatitis B: Long-Term Follow-Up Results for 120 Months.

Entecavir (ETV) may have limited antiviral efficacy in chronic hepatitis B (CHB) patients with a high baseline viral load, especially in cases of partial virologic response (PVR). This study evaluated the outcomes of prolonged ETV monotherapy, given the lack of clear evidence favoring continuation or combination therapy in such scenarios. We included 188 treatment-naïve patients on ETV 0.

Pet Dog Choice in Hong Kong and Mainland China: Exploring Owners' Motivations, Behaviours, and Perceptions.

Dogs are among the most popular pets worldwide, and ownership is increasing in many regions. Responsible pet ownership positively impacts animal welfare, yet little is known about the drivers of pet choices or their regional variation. To address this knowledge gap, a structured online questionnaire was developed to investigate the motivations, behaviours, perceptions, and demography of owners acquiring dogs.

Context-dependent memory in the real world: the role of frequency and context dwell time.

We investigated the context-dependent memory effect outside of the laboratory in order to examine whether the effect impacts everyday memory retrieval. We also examined various factors that may interact with the context-dependent memory effect such as frequency and context dwell time. In the experiment, we used a smartphone app to track participant's GPS locations for 5 weeks.