As others see us.

If it is to be fully effective, functional activity in business needs to see itself as an integral part of management and not as some specialist, separate adjunct. The so-called professions often find this difficult to contemplate, let alone achieve. In Unilever's UK operations, occupational health activity and staff are effectively integrated into general management and, as a direct consequence, the business benefits and the participants reach higher levels of job satisfaction.

Long loops in proteins.

In proteins, loop regions which connect secondary structures are generally short (80% are <10 amino acids long). However, long loops, defined here as > or = 10 residues, do occur. Two types of long loop may be distinguished: those which connect adjacent regions of secondary structure ('long-closed') and those which connect distant secondary structures ('long-open').

The BC loop in poliovirus coat protein VP1: an ideal acceptor site for major insertions.

In poliovirus the BC loop of the VP1 coat protein is hypervariable and can accommodate numerous foreign sequences introduced by genetic engineering. This paper examines the characteristics of the VP1 BC loop of the picornaviruses to see why this loop is so variable and particularly favourable for the insertion of foreign sequences leading to the formation of chimeric particles. The characteristics which make this loop distinctive can be used to find equally permissive loops in other proteins.

Depicting topology and handedness in jellyroll structures.

The jellyroll structure is a special case of the Greek key topology and, to date, has only been observed in complete form in one of its four possible arrangements. Like other elements of super-secondary structure involving the beta-strand (e.g.