Publications by authors named "H J Sharma"
G-quadruplex structures (GQSes) are the intricate molecular knots or marvels that play diverse roles in various cellular processes, such as replication, transcription, and translation, which regulate gene expression. Even though GQSes can be found throughout the genome, they are more prevalent in certain genomic regions like promoters and 5'-UTRs. This review discusses the functionality of GQSes across various regions of the genome and draws attention to the intriguing world of DNA and RNA GQSes.
View Article and Find Full Text PDFMethod development and validation on RP-HPLC method for estimation of xanthohumol in nanostructured lipid carriers drug delivery systems.
J Chromatogr B Analyt Technol Biomed Life Sci
December 2024
Xanthohumol(Xn) is isolated from female inflorescences of Humulus lupulus. It has been discovered that Xn and its formulation are useful in the treatment of cancer. As this bioactive compound has medicinal importance, hence, a novel, precise, and sensitive HPLC method should be developed.
View Article and Find Full Text PDFArticle Synopsis
- Understanding the distribution of the Indian crested porcupine (Hystrix indica) is crucial for conservation efforts in human-dominated landscapes, particularly in the Parsa-Koshi Complex of Nepal.
- Researchers deployed cameras at 154 sites and found moderate occupancy (0.321) and detection probability (0.315) of porcupines, with higher occurrences in protected areas compared to outside.
- The study revealed that porcupine occupancy is positively influenced by agricultural land and human presence, while it decreases with more forest canopy cover, indicating the species' adaptability but also the potential for increased human-wildlife conflicts.
Background & objectives Dengue virus causes frequent outbreaks and epidemics with high morbidity and mortality. It is important to monitor the trends of the dengue virus and its serotypes. We carried out the present work to study the prevalence of the dengue virus and its serotypes in clinically suspected cases of dengue in Rajasthan.
View Article and Find Full Text PDFTotal Serum Immunoglobulin E in a Cohort of Children with Food Allergy.
J Allergy Clin Immunol Pract
December 2024
Background: Total serum immunoglobulin E (TsIgE) has not been examined in children with food allergy.
Objective: Evaluate associations of TsIgE with patient, household, environmental and community-level characteristics among children with food allergy.
Method: Linear mixed effect models of data from 398 Black and/or African American (B/AA) and White and/or European American (W/EA) children with allergist-diagnosed food allergy from the multi-center, observational cohort FORWARD; TsIgE in kU/L was the primary outcome measure.