Epidemiology of high-level parvovirus B19 viraemia among Dutch blood donors, 2003-2009.

Background And Objectives: Plasma derivatives and blood components with low levels of parvovirus B19 (B19) seem not infectious, but recently infected, highly viraemic donors may transmit B19. We studied the incidence of high-level B19 viraemia (B19 DNA>10(6) IU/ml) in 6.5 million Dutch blood donations.

Serological and biochemical identification of HLA-Aw33 subtypes.

In the present study, we show, on the basis of serology, absorption experiments, and one-dimensional isoelectric focusing, that the well-defined HLA-Aw33 antigen can be separated into two subtypes, provisionally called Aw33.1 and Aw33.2, which differ in race distribution and linkage disequilibrium.