Relapse of herpes simplex encephalitis after conventional acyclovir therapy.

Acyclovir sodium is the drug of choice for the treatment of herpes simplex encephalitis. We treated an immunocompetent patient with a ten-day course of intravenous acyclovir sodium at the recommended dosage of 10 mg/kg every eight hours for clinically apparent herpes simplex encephalitis. After marked improvement, his condition deteriorated four days after completing acyclovir therapy.

The first American case of myasthenia gravis.

Reported here is an account of the illness of Indian Chief Opechankanough (died 1644), which may represent the first recognized case of myasthenia gravis. Historical publications based on colonial correspondence with England are the sources for this article. To my knowledge, this is the first article in the medical historical literature to mention this famous and influential Indian.

[Changes in the arteries in the hand and fingers due to vinyl chloride exposure (author's transl)].

The results of angiography of the hand in workers in the vinyl chloride industry are described. Amongst 93 patients, there were 19 on whom angiograms of the hand were performed because of Raynaud-like changes, pain or other pathological findings. All patients examined by angiography showed abnormalities in the vessels in the hands and fingers of varying severity.