Publications by authors named "H J Majima"
Synephrine Inhibits Oxidative Stress and HO-Induced Premature Senescence.
Cell Biochem Biophys
January 2025
Synephrine, a protoalkaloid found in Citrus aurantium (CA) peels, exerts lipolytic, anti-inflammatory, and vasoconstrictive effects; however, its antioxidant activity remains unclear. In this study, electron spin resonance spectroscopy revealed that synephrine scavenged both hydroxyl and superoxide anion radicals. Several external stimuli, such as HO, X-rays, and ultraviolet (UV) radiation, cause stress-induced premature senescence (SIPS).
View Article and Find Full Text PDFD-dimer, a byproduct of cross-linked fibrin degradation, arises during the fibrinolysis process, breaking down blood clots in circulation. This systematic review and meta-analysis aimed to synthesize evidence of D-dimer alteration in people with malaria, including variations in disease severity. The systematic review was registered in PROSPERO with registration number CRD42024528245.
View Article and Find Full Text PDFKorth. Havil (MS) has a traditional use in relieving pain, managing hypertension, treating cough, and diarrhea, and as a morphine substitute in addiction recovery. Its potential in addressing Alzheimer's disease (AD), a neurodegenerative condition with no effective treatments, is under investigation.
View Article and Find Full Text PDFThe universe began 13.8 billion years ago, and Earth was born 4.6 billion years ago.
View Article and Find Full Text PDFArticle Synopsis
- The review focuses on prevention and treatment strategies for COVID-19, highlighting the role of SARS-CoV-2 mutations in creating variants that evade immunity and some antiviral resistance.
- It identifies 150 natural metabolites and botanical drug-derived bioactive molecules that may offer more effective and less toxic alternatives for COVID-19 treatment, including Thai and Chinese traditional medicine approvals.
- The text emphasizes the impact of long COVID on about 10% of patients and suggests that botanical adjuvants, including vitamin C and E, might help alleviate symptoms and reduce the risk of long COVID progression.