Publications by authors named "H J Kunkel"

Article Synopsis
  • Botanicals are being increasingly used in skincare, but there's limited data on how often they cause allergic reactions, specifically allergic contact dermatitis.
  • A study conducted at the Mayo Clinic from 1997 to 2017 analyzed patch test results from over 12,000 individuals, revealing that nearly 11% showed positive reactions to botanical agents.
  • The most common allergen identified was Myroxylon pereirae resin, and patients with reactions to botanicals often had multiple sensitivities, indicating a significant awareness needed for potential allergic responses associated with these products.
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A family of three phase, polymer-ceramic-metal (Poly-cer-met) electrically conducting composites was developed via cold sintering for acoustic matching application in medical ultrasound transducers. A range of acoustic impedance ( Z ) between MRayl with low attenuation (<3.5 dB/mm, measured at 10 MHz) was achieved in composites of zinc oxide, silver, and in thermoplastic polymers like Ultem polyetherimide (PEI) or polytetrafluoroethylene (PTFE) at sintering pressure less than 50 MPa and temperature of 150 °C.

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Article Synopsis
  • Patients with limited English proficiency (LEP) face challenges in end-of-life decision making and advance care planning, which can lead to disparities in their care.
  • A systematic review was conducted, analyzing eight studies from the US and Australia that utilized various interventions, such as trained personnel and multimedia, to address these disparities.
  • While the interventions showed some success in increasing advance directive completion and changing treatment preferences, there are still few options available for LEP patients, and more research is needed to assess the effectiveness of these interventions.
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Heat shock protein 90 (HSP90) stabilizes many client proteins, including the BCR-ABL1 oncoprotein. BCR-ABL1 is the hallmark of chronic myeloid leukemia (CML) in which treatment-free remission (TFR) is limited, with clinical and economic consequences. Thus, there is an urgent need for novel therapeutics that synergize with current treatment approaches.

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