Publications by authors named "H J Buschmann"
Population matrix models are routinely used to study the demography of wild populations and to guide management choices. When vital rates are unknown for a specific population or life history stage, researchers often replace them with estimates from other populations of the same species. Such 'hybrid' matrices might ignore among-population life history variation and lead to incorrect inferences.
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- Regulatory authorities require stability data for drug approval, but traditional analyses are often lengthy and expensive.
- This study introduces a sustainable mechanochemical method for stress-testing five common antihypertensive drugs in the sartan family to create realistic degradation profiles.
- By using high-resolution mass spectrometry, researchers detected impurities and identified significant degradation products within just 15-60 minutes of ball milling, underscoring the method's effectiveness and relevance for solid-state drug stability testing.
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- Zygnematophyceae, a group of filamentous algae, are closely related to land plants, and this study sequenced four of their genomes, creating detailed chromosome-scale assemblies for three strains of Zygnema circumcarinatum.
- The research identified key traits in their common ancestor with land plants that may have enabled plants to adapt to life on land, including expanded genes for signaling, environmental responses, and multicellular growth.
- Additionally, the study revealed shared enzymes for cell wall synthesis between Zygnematophyceae and land plants, suggesting a genetic framework that integrates environmental responses with developmental growth over 600 million years of evolution.
Streptophytes are best known as the clade containing the teeming diversity of embryophytes (land plants). Next to embryophytes are however a range of freshwater and terrestrial algae that bear important information on the emergence of key traits of land plants. Among these, the Klebsormidiophyceae stand out.
View Article and Find Full Text PDFRecalls of medicinal products can cause supply bottlenecks. This is often due to the findings of unexpected impurities that pose a health risk to patients. A recent example is losartan potassium which was contaminated with azido-impurities.
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