Purpose: This study introduces a retrospective analysis of the surgical management of 213 consecutive cases of cervical spine metastases and Multiple Myeloma Cases.
Materials And Methods: Retrospective analysis of prospectively collected data in a single surgical center of patients who underwent surgery for tumors of the cervical spine between 1994 and 2017. Exclusion criteria were intradural tumors and primary tumors.
Hyaluronic acid, a biocompatible polymer, holds significant potential for drug delivery applications. Its variable degree of protonation, which entails tunable physical properties, makes it an ideal candidate for developing pH-sensitive hydrogels. Like other smart drug delivery systems, pH-responsive hydrogels can enhance medical treatment and expedite the healing process.
View Article and Find Full Text PDFMyeloid-derived suppressor cells (MDSC) are a heterogeneous cell population of incompletely differentiated immune cells. They are known to suppress T cell activity and are implicated in multiple chronic diseases, which make them an attractive cell population for drug discovery. Here, we characterized the baseline proteomes and phospho-proteomes of mouse MDSC differentiated from a progenitor cell line to a depth of 7000 proteins and phosphorylation sites.
View Article and Find Full Text PDFPurpose: There is an increased demand for surgical solutions to treat craniocervical instability. This retrospective study demonstrates the clinical and radiological outcomes of unstable craniocervical junction treated with occipitocervical fusion.
Material And Methods: The mean age of 52 females and 48 males was 56.