Publications by authors named "H J Bennett"
This study examined nine prominent commercially available single-cell RNA sequencing (scRNA-seq) kits across four technology groups. Each kit was characterized using peripheral blood mononuclear cells (PBMCs) from a single donor, which enabled consistent assessment of factors such as analytical performance, protocol duration and cost. The Chromium Fixed RNA Profiling kit from 10× Genomics, with its probe-based RNA detection method, demonstrated the best overall performance.
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- Static stretching is commonly used to improve flexibility, but there's no clear consensus on the best way to do it in terms of frequency, intensity, or volume.
- A systematic review of 189 studies with over 6,600 adults found that both acute and chronic static stretching significantly increased flexibility, with chronic stretching showing a larger effect.
- The research indicated that factors like age, sex, and training status did not significantly influence flexibility outcomes, although those with poor initial flexibility saw greater improvements compared to those with average flexibility.
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- A study was conducted to explore the links between physical function tests and frailty in older adults living in the community, specifically examining how being overweight or obese might strengthen this association.
- The research measured the mobility, balance, strength performance, and frailty status of 161 participants, using logistic regression to analyze the data.
- Results indicated that both high body mass index (BMI) and poor performance in physical function tests, like the timed up and go (TUG), are significantly associated with frailty, especially when they occur together, suggesting these factors should be vital in frailty prevention strategies.
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- The study aimed to investigate the cardiac structure and function of professional Australian jockeys compared to the general population, focusing on the impacts of the physically demanding nature of thoroughbred racing.
- Results showed that jockeys are smaller and lighter but have larger left ventricular (LV) end diastolic volume and LV mass index, indicating cardiac adaptations likely due to their profession.
- Although the overall global longitudinal strain (GLS) was similar between the two groups, 17% of jockeys exhibited an abnormal GLS, suggesting potential cardiovascular issues among some jockeys.
Multiomic profiling of single cells by sequencing is a powerful technique for investigating cellular diversity. Existing droplet-based microfluidic methods produce many cell-free droplets, underutilizing bead barcodes and reagents. Combinatorial indexing on microplates is more efficient for barcoding but labor-intensive.
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