Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune encephalitis characterized by psychiatric and neurological symptoms. It often presents as a paraneoplastic manifestation and is rarely associated with small cell lung cancer. While treatment usually involves immunotherapy and treatment of underlying malignancy, the patient's condition can complicate treatment decisions.
View Article and Find Full Text PDFBackground: Pneumococcal vaccines have been available worldwide since the early 2000s; consequently, few reports exist of poststreptococcal acute glomerulonephritis (PSAGN) or complications of pneumococcal infection. We describe a patient with PSAGN and bacteremia with Streptococcus pneumoniae serotype 22F (not covered by the 13-valent pneumococcal vaccine (PCV 13)).
Case Diagnosis/treatment: A 5-year-old boy received the PCV13 vaccine and was admitted to our hospital with a fever and gross hematuria.
Coronavirus disease (COVID-19), a viral infection caused by severe acute respiratory syndrome coronavirus 2, was first reported in China in December 2019 and has since become a global pandemic. COVID-19 is a multisystem disease with respiratory symptoms as the main presentation. There is growing awareness of the adverse prognostic impact of cardiovascular involvement caused by COVID-19.
View Article and Find Full Text PDFBackground: Systemic baricitinib and corticosteroids play important roles in treating severely and critically ill patients with coronavirus disease 2019 (COVID-19). However, the efficacy of the combination of baricitinib and corticosteroids compared to that of corticosteroid monotherapy in severely and critically ill hospitalized patients with COVID-19 remains unclear.
Methods: We analyzed severely and critically ill hospitalized patients with COVID-19 aged >18 years between January 1, 2020 and May 31, 2023, using a Japanese multicenter inpatient database.