Publications by authors named "H Ishino"
A 23-year-old man was diagnosed with Crohn's disease (CD) of the large intestine after colonoscopy revealed longitudinal ulcers, and pathology revealed non-caseating epithelioid cell granulomas and anal fistulas. The CD relapsed, and therefore prednisolone (PSL) and infliximab (IFX) treatment was initiated. The PSL was gradually tapered.
View Article and Find Full Text PDFUlcerative colitis (UC) is a chronic inflammatory disorder of the large intestine. Data on the comparative effectiveness of biological therapies such as vedolizumab (VDZ) and ustekinumab (UST) remain limited. This retrospective study compared the effectiveness and safety of VDZ and UST in UC patients.
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- The study analyzed 5804 days of Super-Kamiokande data from 1996 to 2018 to detect variations in solar ^{8}B neutrino flux.
- The researchers utilized a five-day interval measurement approach and employed maximum likelihood and Lomb-Scargle methods to find any periodic modulations.
- They found a significant modulation related to Earth's elliptical orbit around the Sun, with measurements of eccentricity and perihelion shift aligning with astronomical data.
Article Synopsis
- * In a study of 88 UC patients who received UST, remission rates were 66% at 8 weeks and 70.2% at 56 weeks, with better outcomes for those who had never used other biologics compared to those who had failed previous treatments.
- * Factors influencing successful remission with UST included being female, having a low body mass index, and a low lymphocyte-to-monocyte ratio, indicating UST's potential effectiveness for moderate-to-severe UC cases.