Publications by authors named "H Isayama"
We started a registry for cases of immunoglobulin (Ig)G4-related disease (IgG4-RD) in December 2019 to clarify the clinical profile of IgG4-RD. In this study, clinical information from 854 cases registered by February 16, 2024 was analyzed from multiple perspectives. Diagnosis of IgG4-RD was made in 808 cases, comprising 638 definite, 38 probable, and 132 possible.
View Article and Find Full Text PDFBackground And Aims: Endoscopic ultrasound (EUS)-guided transmural drainage with on-demand endoscopic necrosectomy (EN) is increasingly utilized to manage walled-off necrosis (WON). It has not been fully elucidated how EN and its timing are correlated with treatment outcomes compared to the drainage-based approach.
Methods: Within a multi-institutional cohort of 423 patients with pancreatic fluid collections including 227 patients with WON, we identified 153 patients who received the step-up treatment following the initial EUS-guided drainage of symptomatic WON, including 102 EN patients and 51 non-EN (drainage) patients.
Article Synopsis
- The study aimed to validate anti-integrin αvβ6 autoantibodies as a diagnostic biomarker for primary sclerosing cholangitis (PSC) using a new ELISA Kit across multiple hospitals.
- The research involved 81 PSC patients and 358 controls, finding a strong correlation between two testing methods and demonstrating high sensitivity (82.7%) and specificity (94.4%) for diagnosing PSC.
- The presence of these autoantibodies was particularly pronounced in PSC patients without inflammatory bowel disease, highlighting their potential as a reliable biomarker for PSC.
Background And Aims: EUS-guided hepaticogastrostomy (EUS-HGS) carries a risk of serious adverse events (AEs). A newly designed, partially covered laser-cut stent with antimigration anchoring hooks and a thin tapered tip (7.2F), called a Hook stent (Zeon Medical, Tokyo, Japan), has been developed to prevent serious AEs associated with EUS-HGS.
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