Publications by authors named "H Isaji"

Article Synopsis
  • Pyoderma gangrenosum (PG) is a severe skin condition that mainly causes deep ulcers in the legs, and adalimumab is the first approved treatment for it in Japan.
  • A study involving 67 patients assessed the safety and effectiveness of adalimumab, finding that most patients were older and had other health issues; 18.9% experienced adverse reactions.
  • After 12 weeks, around 42.9% of patients showed significant improvement in their condition, suggesting adalimumab is generally well tolerated, but further research is needed for long-term insights.
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Background: Return-to-work (RTW) programs are provided as rehabilitation for people who have taken sick leave from work because of mental health problems. However, methods to present this information to workplaces objectively remain limited.

Objective: This study aimed to conduct an exploratory investigation of the relationship between duration of sick leave and time variation of words used in RTW programs for depression from textual data collected from electronic medical records as a new evaluation indicator.

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The actual use of heated tobacco products (HTPs) among smokers with rheumatoid arthritis (RA) is little known. The objective of this study was to clarify the prevalence and reasons for HTP use among smokers with RA. We administered a web survey to a research company panel in Japan between December 2020 and January 2021.

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We describe a 29-year-old male with thyroid hormone resistance. He was first seen because of a goiter, and was considered to have hyperthyroid Graves' disease. Despite subtotal thyroidectomy followed by radioiodine therapy, serum thyroxine levels were elevated with high serum TSH levels.

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