Synephrine Inhibits Oxidative Stress and HO-Induced Premature Senescence.

Synephrine, a protoalkaloid found in Citrus aurantium (CA) peels, exerts lipolytic, anti-inflammatory, and vasoconstrictive effects; however, its antioxidant activity remains unclear. In this study, electron spin resonance spectroscopy revealed that synephrine scavenged both hydroxyl and superoxide anion radicals. Several external stimuli, such as HO, X-rays, and ultraviolet (UV) radiation, cause stress-induced premature senescence (SIPS).

The Roles of Mitochondria in Human Being's Life and Aging.

The universe began 13.8 billion years ago, and Earth was born 4.6 billion years ago.

Eichner classification based on panoramic X-ray images using deep learning: A pilot study.

Background: Research using panoramic X-ray images using deep learning has been progressing in recent years. There is a need to propose methods that can classify and predict from image information.

Objective: In this study, Eichner classification was performed on image processing based on panoramic X-ray images.

Mitochondria Play Essential Roles in Intracellular Protection against Oxidative Stress-Which Molecules among the ROS Generated in the Mitochondria Can Escape the Mitochondria and Contribute to Signal Activation in Cytosol?

Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability coefficient (Pm) (cm s), are listed for hydrogen peroxide (HO), hydroxyl radical (•OH), superoxide (O), hydroperoxyl radical (HO•), nitric oxide (•NO), nitrogen dioxide (•NO), peroxynitrite (ONOO), and peroxynitrous acid (ONOOH) in comparison to those for water (HO). O is generated from the mitochondrial electron transport chain (ETC), and several other ROS and RNS can be generated subsequently.