Publications by authors named "H Ikushima"
Purpose: This study aims to compare treatment plans created using RapidPlan and PlanIQ for twelve patients with prostate cancer, focusing on dose uniformity, dose reduction to organs at risk (OARs), plan complexity, and dose verification accuracy. The goal is to identify the tool that demonstrates superior performance in achieving uniform target dose distribution and reducing OAR dose, while ensuring accurate dose verification.
Methods: Dose uniformity in the planning target volume, excluding the rectum, and dose reduction in the OARs (the rectum and bladder) were assessed.
Article Synopsis
- Two patients with paroxysmal atrial fibrillation developed pulmonary vein stenosis (PVS) after AF ablation, with Case 1 being a female in her 50s and Case 2 a male in his 60s.
- The first patient showed high-degree left superior PVS 15 months post-ablation, while the second had progressive PVS nine months later, confirmed through contrast-enhanced CT and ventilation-perfusion scans.
- PVS is a rare complication of AF ablation that can lead to severe issues if untreated, and the case report emphasizes the importance of V/Q scans in assessing PVS despite its common association with pulmonary embolism evaluations.
Background/aim: New treatment agents for advanced non-small cell lung carcinoma (NSCLC) have improved overall survival (OS) in the last 20 years. Nevertheless, treatment strategies for patients with NSCLC and pulmonary fibrosis have not yet been established. This study aimed to evaluate OS improvement in patients with stage IV NSCLC based on the underlying pulmonary diseases.
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- The study investigates the use of comprehensive genomic profiling (CGP) in cancer treatment, aiming to improve precision medicine by identifying patient characteristics that predict successful outcomes from CGP.
- Using machine learning on data from almost 61,000 patients in Japan, researchers developed models to predict the identification of effective therapies based on specific cancer types and age groups.
- Results showed that 18.5% of patients had genome-matched therapies identified, with significant predictors including cancer type, age, and presence of liver metastasis, highlighting factors that could guide future applications of CGP in clinical practice.
Article Synopsis
- Brachytherapy (BT), particularly high dose rate (HDR) BT, has become more complex due to advanced techniques, necessitating significant training for radiotherapy technologists and medical physicists (RTMPs).
- A survey conducted across 837 radiation treatment facilities in Japan revealed varying working times for HDR procedures and low quality control (QC) implementation rates for BT compared to external beam radiation therapy (EBRT).
- The findings underscore a need for improved training and education for RTMPs to enhance the quality and safety of BT practices in Japan.