Publications by authors named "H Ideta"

Calcium phosphate-based synthetic bone is broadly used for the clinical treatment of bone defects caused by trauma and bone tumors. Synthetic bone is easy to use; however, its effects depend on the size and location of the bone defect. Many alternative treatment options are available, such as joint arthroplasty, autologous bone grafting, and allogeneic bone grafting.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the correlation between re-ossification after palliative radiotherapy for spinal bone metastases and the preservation of vertebral body height in patients with osteolytic changes.
  • - Conducted as a retrospective observational study, it analyzed 111 vertebral bodies from 54 patients who underwent treatment between 2016 and 2020, using CT images to assess re-ossification and changes in vertebral height.
  • - Results showed that 62.2% of the vertebral bodies exhibited re-ossification, typically confirmed by CT about two months post-radiotherapy, with identified factors influencing vertebral height reduction noted before treatment.
View Article and Find Full Text PDF

Background: This study aimed to investigate changes in muscle strength and functional outcome before and after surgery for soft-tissue sarcoma of the thigh and to examine the timing of recovery.

Methods: From 2014 to 2019, 15 patients who underwent multiple resections of the thigh muscle for soft-tissue sarcoma of the thigh were included in this study. The muscle strength was measured with an isokinetic dynamometer for the knee joint and with a hand-held dynamometer for the hip joint.

View Article and Find Full Text PDF

Nanomaterials show great promise as bone regeneration materials. They can be used as fillers to strengthen bone regeneration scaffolds, or employed in their natural form as carriers for drug delivery systems. A variety of experiments have been conducted to evaluate the osteogenic potential of bone regeneration materials.

View Article and Find Full Text PDF

Various risk factors and causative genes of osteosarcoma have been reported in the literature; however, its etiology remains largely unknown. Bone formation is a shared phenomenon in all types of osteosarcomas, and sclerostin is an extracellular soluble factor secreted by osteocytes that prevents bone formation by inhibiting the Wnt signaling pathway. We aimed to investigate the antitumor effect of sclerostin against osteosarcoma.

View Article and Find Full Text PDF