Publications by authors named "H I Sair"
Neurological recovery in individuals with spinal cord injury (SCI) is multifaceted, involving mechanisms such as remyelination and perilesional spinal neuroplasticity, with cortical reorganization being one contributing factor. Cortical reorganization, in particular, can be evaluated through network (graph) analysis of interregional functional connectivity. This study aimed to investigate cortical reorganization patterns in persons with chronic SCI using a multilayer community detection approach on resting-state functional MRI data.
View Article and Find Full Text PDFArticle Synopsis
- Resting-state functional MRI (rs-fMRI) is gaining traction in clinical settings for brain mapping, but faces challenges with standardization, reliability, and interpretation of results across different medical centers.
- Key issues include variability in cognitive network representation and the effects of neurovascular uncoupling, which affect the accuracy of language lateralization and overall connectivity detection.
- Despite these challenges, rs-fMRI is viewed as a valuable complement to task-based fMRI (tb-fMRI) in clinical presurgical contexts and is expected to grow in use as solutions to its limitations are developed.
Article Synopsis
- Oligodendroglioma is a brain tumor characterized by specific genetic mutations and treatments typically involve surgery followed by either observational care or a combination of radiation and chemotherapy.
- This study analyzed data from 277 patients with IDH-mutant, 1p/19q codeleted oligodendrogliomas to examine the impact of different adjuvant treatment regimens on progression-free survival (PFS).
- Results indicated that patients with grade 3 tumors showed significantly longer PFS when treated with radiation and PCV chemotherapy compared to those receiving radiation with TMZ or no adjuvant therapy, emphasizing the need for more research in this area.
Background: Early detection of acute brain injury (ABI) at the bedside is critical in improving survival for patients with extracorporeal membrane oxygenation (ECMO) support. We aimed to examine the safety of ultra-low-field (ULF; 0.064-T) portable magnetic resonance imaging (pMRI) in patients undergoing ECMO and to investigate the ABI frequency and types with ULF-pMRI.
View Article and Find Full Text PDFBackground: While the diagnosis of frontotemporal dementia (FTD) is based mostly on clinical features, [F]-FDG-PET has been investigated as a potential imaging standard in ambiguous cases, with arterial spin-labeling (ASL) MRI gaining recent interest.
Purpose: The purpose of this study is to conduct a systematic review and meta-analysis on the diagnostic performance of ASL MRI in patients with FTD and compare it with that of [F]-FDG-PET.
Data Sources: A systematic search of PubMed, Scopus, and Embase was conducted until March 13, 2024.