COMPREHENSIVE STUDY OF ANTIOXIDANT ACTIVITY OF OXALIC ACID DIAMIDE DERIVATIVES AND THEIR EFFECT ON THE CONCENTRATION OF MALONIC DIALDEHYDE IN THE BRAIN AND LIVER TISSUES OF WHITE RATS.

Unlabelled: The wide range of chemical structures of antioxidants provides opportunities for individual selection of the most suitable compounds, taking into account the unique needs and characteristics of the body. Synthetic antioxidants can be specially designed with certain characteristics, which helps to create more effective and stable compounds. The aim of this work was to conduct a series of studies to identify the antioxidant activity of newly synthesized compounds of a number of oxalic acid diamides based on 3,4-dimethoxyphenylcyclopentylamine N1 ((1-3,4-dimethoxyphenyl)methyl)-N2-(2-methoxyphenyl)oxalamide on the content of malondialdehyde (MDA) in the brain and liver tissues of white rats (in vivo, in vitro), as well as to determine their potential pharmacological properties that correspond to Lipinsky's "Rule of Five" (in silico).