Publications by authors named "H Huldani"
Background: Renal ischemia-reperfusion injury (RIRI) is a critical phenomenon that compromises renal function and is the most serious health concern related to acute kidney injury (AKI). Pioglitazone (Pio) is a known agonist of peroxisome proliferator-activated receptor-gamma (PPAR-γ). PPAR-γ is a nuclear receptor that regulates genes involved in inflammation, metabolism, and cellular differentiation.
View Article and Find Full Text PDFImmunometabolism, which studies cellular metabolism and immune cell function, is a possible cancer treatment. Metabolic pathways regulate immune cell activation, differentiation, and effector functions, crucial to tumor identification and elimination. Immune evasion and tumor growth can result from tumor microenvironment metabolic dysregulation.
View Article and Find Full Text PDFDiabetic wound is one of the main challenges in dermatology. Although stem cell-based treatment has therapeutic benefits in wound repair, the clinical application is still limited. Herein we investigated whether adipose stem cells -derived exosomes (Exo) loaded on hyaluronic acid (HA) could promote healing in diabetic rats.
View Article and Find Full Text PDFOvarian cancer poses significant challenges and remains a highly lethal disease with limited treatment options. In the context of ovarian cancer, interleukins (ILs) and interferons (IFNs), important cytokines that play crucial roles in regulating the immune system, have emerged as significant factors influencing its development. This article provides a comprehensive review of the involvement of various ILs, including those from the IL-1 family, IL-2 family, IL-6 family, IL-8 family, IL-10 family, and IL-17 family, in ovarian cancer.
View Article and Find Full Text PDFArticle Synopsis
- Long non-coding RNAs (lncRNAs) are gaining attention in cancer research, though there's still debate on how many functional non-coding RNAs exist and their roles in cells.
- Small nucleolar RNAs (snoRNAs), which are shorter and found mostly in the nucleolus, have been studied more extensively and are often encoded within introns of genes known as small nucleolar RNA host genes (SNHGs).
- The article delves into the biology of SNHGs, their significance in human cancers, and discusses the potential of snoRNAs as prognostic and diagnostic tools in various cancer types.