Publications by authors named "H Horii"

For renewal-reward processes with a power-law decaying waiting time distribution, anomalously large probabilities are assigned to atypical values of the asymptotic processes. Previous works have revealed that this anomalous scaling causes a singularity in the corresponding large deviation function. In order to further understand this problem, we study in this article the scaling of variance in several renewal-reward processes: counting processes with two different power-law decaying waiting time distributions and a Knudsen gas (a heat conduction model).

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Immunomodulators (tocilizumab/baricitinib) improve outcomes of coronavirus disease 2019 (COVID-19) patients, but the synergistic effect of remdesivir is unknown. The effect of combination therapy with remdesivir, immunomodulators, and standard treatment in COVID-19 patients was investigated. This retrospective, single-center study included COVID-19 patients who were treated with tocilizumab or baricitinib.

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Pulmonary artery agenesis (PAA) is a rare congenital vascular anomaly usually diagnosed during infancy. We herein report a 67-year-old man with PAA manifesting as massive hemoptysis. Contrast-enhanced computed tomography of the chest revealed the diagnosis of PAA, which we speculated to have resulted in the present event.

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Article Synopsis
  • Tocilizumab and baricitinib have been found to help improve outcomes for COVID-19 patients, but a direct comparison of their effectiveness had not been done until this study.
  • A retrospective study conducted at Hokkaido University Hospital analyzed data from 98 COVID-19 patients who received either drug, revealing no significant differences in all-cause mortality or respiratory improvement after 28 days of treatment.
  • Key factors influencing patient outcomes included age and chronic renal disease, while patient treatment with either drug showed similar rates of secondary infections, suggesting both could be equally effective in treating COVID-19.
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We present three cases with an atypical clinical course of organizing pneumonia (OP) secondary to coronavirus disease 2019 (COVID-19). Three patients were discharged with satisfactory improvement after standard steroid therapy for COVID-19. Shortly after the completion of treatment, the patients experienced a flare-up of symptoms.

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