Publications by authors named "H Hisai"
Background: Gastric anisakiasis typically causes severe abdominal symptoms; however, we incidentally detected asymptomatic gastric anisakiasis cases during esophagogastroduodenoscopy. The factors associated with developing acute abdominal symptoms induced by gastric anisakiasis remain unclear. Therefore, this study aimed to investigate the clinical factors associated with abdominal symptoms of gastric anisakiasis by comparing symptomatic and asymptomatic cases.
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- Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is essential for diagnosing pancreatic tumors, and this study focused on needle tract seeding (NTS) occurrences post-EUS-TA in Japan.
- A survey of over 12,000 patients revealed an overall NTS incidence of 0.330%, notably higher in those with pancreatic ductal adenocarcinomas (PDACs) compared to other tumors.
- NTS was only found after transgastric procedures, with the majority located in the gastric wall, and patients who underwent resection of NTS lesions had significantly better survival rates.
Background And Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is used for the histopathological diagnosis of any type of gastrointestinal disease. Few adverse events are experienced with this procedure; however, the actual rate of adverse events remains unclear. This study aimed to clarify the current status of cases that experienced adverse events related to the EUS-FNA procedure used for histopathologic diagnoses.
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- The study analyzed how digital image analysis (IA) of Ki-67 staining can improve prognostic predictions for gastrointestinal stromal tumors (GIST) alongside modified NIH classifications in 92 patients.
- Researchers compared two image analysis methods: whole slide imaging (WSI) and manually captured images (MCI), and identified effective Ki-67 cutoff values that correlate with recurrence-free survival (RFS).
- Findings indicated that Ki-67 quantitation is a strong predictor of prognosis, potentially outperforming traditional NIH classification in determining patient risk levels, making IA a valuable tool for better patient management in GIST cases.
Backgrounds & Aims: We aimed to clarify the characteristics of resistance-associated substitutions (RASs) after treatment failure with NS5A inhibitor, daclatasvir (DCV) in combination with NS3/4A inhibitor, asunaprevir (ASV), in patients with chronic hepatitis C virus genotype 1b infection.
Methods: This is a nationwide multicenter study conducted by the Japanese Red Cross Liver Study Group. The sera were obtained from 68 patients with virological failure after 24 weeks of DCV/ASV treatment.