Publications by authors named "H Hirukawa"
Article Synopsis
- This study aimed to compare the effects of two diabetes medications, SGLT2 inhibitors (luseogliflozin) and DPP-4 inhibitors (teneligliptin), on β-cell function in type 2 diabetes patients over 26 weeks.
- A total of 103 participants were included, with results showing improvements in the disposition index (a measure of insulin effectiveness) for both groups, but with more significant alleviation of β-cell dysfunction in the luseogliflozin group.
- The findings suggest that while both drugs improve insulin secretion and sensitivity, luseogliflozin may be more effective at reducing β-cell dysfunction compared to teneligliptin.*
Neoadjuvant chemotherapy(NAC)is prescribed for resectable esophagogastric junctional cancer on the basis of esophageal invasion length, lymph node metastasis, and pathological diagnosis. Due to a lack of consensus in Japan, however, discussion regarding its use is necessary. This study comprised 6 patients who underwent surgical resection after receiving NAC in our department from 2018 to 2022.
View Article and Find Full Text PDFSecondary aortoenteric fistula (sAEF) is a rare but serious complication after open aortic aneurysm repair (OAR). Although there is no consensus on the treatment strategy for sAEF, acute management of bleeding and infection control greatly affect the outcome. We report five cases of sAEF following OAR from 2016 to 2021.
View Article and Find Full Text PDFBackground: Recent improvements in systemic chemotherapy have provided an opportunity for patients with stage IV gastric cancer (GC) to undergo conversion surgery (CS). The aim of this study was to evaluate the long-term outcomes of patients who underwent CS and to elucidate the prognostic factors for CS in stage IV GC.
Methods: A total of 79 patients who underwent CS with the aim of R0 resection for stage IV GC at six institutions from January 2008 to July 2019 were enrolled.
Non-islet cell tumor hypoglycemia (NICTH) is a paraneoplastic syndrome that causes severe hypoglycemia. The tumor involved produces high-molecular-weight insulin-like growth factor-II (IGF-II). NICTH can be caused by various benign and malignant tumors.
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