Background: Digital breast tomosynthesis (DBT) has been widely adopted as a supplemental imaging modality for diagnostic evaluation of breast cancer and confirmation studies. In this study, a deep learning-based method for characterizing breast tissue patterns in DBT data is presented.
Methods: A set of 5388 2D image patches was produced from 230 right mediolateral oblique, 259 left mediolateral oblique, 18 right craniocaudal, and 15 left craniocaudal single-breast DBT studies, using slice-wise annotations of abnormalities and normal tissue.
Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy coupled with machine learning-based partial least squares discriminant analysis (PLS-DA) was applied to study if severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be detected from nasopharyngeal swab samples originally collected for polymerase chain reaction (PCR) analysis. Our retrospective study included 558 positive and 558 negative samples collected from Northern Finland. Overall, we found moderate diagnostic performance for ATR-FTIR when PCR analysis was used as the gold standard: the average area under the receiver operating characteristics curve (AUROC) was 0.
View Article and Find Full Text PDFIn interior computed tomography (CT), the x-ray beam is collimated to a limited field-of-view (FOV) (e.g. the volume of the heart) to decrease exposure to adjacent organs, but the resulting image has a severe truncation artifact when reconstructed with traditional filtered back-projection (FBP) type algorithms.
View Article and Find Full Text PDFPrevious research has shown that gaze cues facilitate responses to an upcoming target if the target location is compatible with the direction of the cue. Similar cueing effects have also been observed with central arrow cues. Both of these cueing effects have been attributed to a reflexive orienting of attention triggered by the cue.
View Article and Find Full Text PDFThis study reports of the novel water-induced shape-memory of bioabsorbable poly(D,L-lactide). We have developed an orientation-based programming process that generates an ability for poly(D,L-lactide) to transform its shape at 37°C in an aqueous environment without external energy and to adapt to a predefined stress level by stress generation or relaxation. In this orientation-programming process, polymer material is deformed and oriented at an elevated temperature and subsequently cooled down while retaining its deformed shape, tension, and polymer chain entanglements.
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