Publications by authors named "H Heers"
Introduction: Ureterovascular fistula (UVF) is a rare but potentially life-threatening condition. Since its primary description by Moschkowitz in 1908, many case reports, studies and reviews have been written about this condition with the suggestive symptoms and risk factors repeatedly discussed. This study will be focusing on the different locations of 532 out of 605 fistulae published from 1908 up to 2022 besides eight new patients of our own.
View Article and Find Full Text PDFPurpose: Despite many efforts, no reliable urinary marker system has so far shown the potential to substitute cystoscopy. Measuring volatile organic compounds (VOCs) from urine is a promising alternative. VOCs are metabolic products which can be measured from the headspace of urine samples.
View Article and Find Full Text PDFPurpose: The anti-NECTIN4 antibody-drug conjugate enfortumab vedotin (EV) is approved for patients with metastatic urothelial cancer (mUC). However, durable benefit is only achieved in a small, yet uncharacterized patient subset. is located on chromosome 1q23.
View Article and Find Full Text PDFA deep-learning workflow to predict upper tract urothelial carcinoma protein-based subtypes from H&E slides supporting the prioritization of patients for molecular testing.
J Pathol Clin Res
March 2024
Article Synopsis
- Upper tract urothelial carcinoma (UTUC) is a rare and aggressive cancer that differs from more common bladder urothelial carcinoma, which has identifiable molecular subtypes and targeted therapies.
- Researchers identified protein-based subtypes of UTUC tumors using deep learning models that analyze routine histopathological slides, allowing for better prediction of tumor characteristics.
- The study found significant links between the predicted subtypes and key tumor features, including shape, histological type, and important biomarkers like PD-L1 and FGFR3 mutations, which could guide future treatment approaches.