Preoperative dorsal disc height is a predictor of indirect decompression effect through oblique lateral interbody fusion in lumbar degenerative stenosis.

The extent of indirect decompression after oblique lateral interbody fusion (OLIF) is one of the most important factors in deciding the strategy. To assess the radiographical predictors of the effect of indirect decompression in patients with lumbar degenerative spondylosis by OLIF. Thirty-two consecutive patients who underwent OLIF at 58 lumbar disc levels were enrolled in this study.

New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety.

The identification, structure-activity relationships (SARs), and biological effects of new antimalarials consisting of a 2,3,4,9-tetrahydro-1H-β-carboline core, a coumarin ring, and an oxyalkanoyl linker are described. A cell-based phenotypic approach was employed in this search for novel antimalarial drugs with unique modes of action. Our screening campaign of the RIKEN compound library succeeded in the identification of the known tetrahydro-β-carboline derivative (4e) as a hit compound showing significant in vitro activity.

Condensed Film Formation and Molecular Packing in Cationic Surfactant-Cholesterol and Zwitterionic Surfactant-Cholesterol Systems at the Hexane/Water Interface.

A condensed film formation of surfactants with a charged head group at the oil/water interface was achieved by mixing surfactants of different geometric shapes to control molecular packing at the interface. The adsorbed films of mixed tetradecyltrimethylammonium bromide (C14TAB)-cholesterol (Chol) and tetradecylphosphocholine (C14PC)-Chol systems at the hexane/water interface were examined by interfacial tension and X-ray reflectivity measurements. The interfacial tension versus Chol concentration curves have break points because of the expanded-condensed phase transition of the adsorbed film.

Solid Film Formation at the Tetradecane/Aqueous Hexadecyltrimethylammonium Bromide Solution Interface Studied by Interfacial Tensiometry and X-ray Reflectometry.

The effect of oil on condensed film formation in the adsorbed film of hexadecyltrimethylammonium bromide (C16TAB) at the tetradecane (C14)/water (W) interface was examined by interfacial tension and X-ray reflectivity measurements. The interfacial tension vs temperature curves have break point due to the expanded?condensed phase transition of the adsorbed film. The partial molar entropy of C16TAB at the interface changes discontinuously, whereas the interfacial density changes almost continuously at the phase transition point.

Microdiscectomy and Foraminotomy in Cervical Spondylotic Myelopathy and Radiculopathy.

This study was to assess the efficacy of microdiscectomy, cage fixation, and right tranuncal foramintomy for the patients suffering from right radiulo-myelopathy. Anterior cervical foraminotomy was reported to be an effective option for the treatment of cervical degenerative radiculopathy but with the problem of recurrence. Since Hakuba reported the method of trans-unco-discal approach in 1976, it was designed as keyhole foraminotomy which was called transuncal approach, transpedicular approach or transvertebral approach.