Combined effects of reflexology massage and respiratory relaxation on pain following chest tube removal in heart surgery patients.

Background And Aim: Removing the chest tube in cardiac patients after surgery is one of the worst experiences of hospitalization in the intensive care units. Various pharmacological and non-pharmacological methods are available to control pain in these patients. This study aimed to investigate the combined effect of reflexology massage and respiratory relaxation on pain following chest tube removal in cardiac surgery patients of Shahid Beheshti Hospital in Shiraz, Iran, in 2023.

Determinants of increased muscle insulin sensitivity of exercise-trained versus sedentary normal weight and overweight individuals.

The athlete's paradox states that intramyocellular triglyceride accumulation associates with insulin resistance in sedentary but not in endurance-trained humans. Underlying mechanisms and the role of muscle lipid distribution and composition on glucose metabolism remain unclear. We compared highly trained athletes (ATHL) with sedentary normal weight (LEAN) and overweight-to-obese (OVWE) male and female individuals.

Paternal addiction to cigarettes, alcohol, and opium and the psychological distress of their youths in southeast Iran.

Previous studies have reported inconsistent findings regarding paternal addiction to cigarettes, alcohol, and opium with psychological distress in youths. This study examined the association between paternal addiction to cigarettes, alcohol, and opium and the psychological distress of youths in southeast Iran. This cross-sectional study was conducted on 895 youths (aged 15-35) from the baseline phase of the Rafsanjan Youth Cohort Study (RYCS) whose fathers also participated in the Rafsanjan Cohort Study (RCS).

B-cell-Specific Moloney Murine Leukemia Virus Integration Site 1 and Fas Ligand Expression in Colorectal Cancer Progression and Prognosis.

Background: B-cell-specific Moloney murine leukemia virus integration site 1 (BMI1) and Fas ligand (FasL) are two critical stemness genes believed to play a role in the development of colorectal cancer (CRC). This study aimed to investigate the expression levels of these genes in primary CRC tumors to assess their correlation with cancer progression and prognosis.

Methods: The relative expression levels of BMI1 and FasL were analyzed using real-time polymerase chain reaction in 100 primary CRC tumor samples along with paired adjacent non-cancerous tissues.

The role of exosomes for sustained specific cardiorespiratory and metabolic improvements in males with type 2 diabetes after detraining.

Background: High-intensity interval training (HIIT) has been shown to improve cardiorespiratory fitness (V˙O max) but may ameliorate insulin sensitivity only in insulin-resistant humans. It is yet unclear whether these benefits persist after detraining and to which extent duration and effectiveness of metabolic improvements differ between individuals without and with prediabetes or type 2 diabetes (T2D). Understanding these differences is relevant for developing targeted exercise training modes for individuals with different stages of dysglycemia.