Association of corneal endothelial cell morphology with neurodegeneration in mild cognitive impairment and dementia.

Introduction: Corneal confocal microscopy (CCM) detects neurodegeneration in mild cognitive impairment (MCI) and dementia and identifies subjects with MCI who develop dementia. This study assessed whether abnormalities in corneal endothelial cell (CEC) morphology are related to corneal nerve morphology, brain volumetry, cerebral ischemia, and cognitive impairment in MCI and dementia.

Methods: Participants with no cognitive impairment (NCI), MCI, and dementia underwent CCM to quantify corneal endothelial cell density (CECD) and area (CECA), corneal nerve fiber morphology, magnetic resonance imaging (MRI) brain volumetry, and severity of brain ischemia.

Evaluating the Efficacy of Common Femoral Endarterectomy With Profundoplasty: A Three-Year Single-Center Perspective.

Background: This study aims to synthesise recent findings on the outcomes of common femoral endarterectomy (CFE) with profundoplasty, evaluating the efficacy, complications, and predictors of long-term success in patients undergoing this procedure.

Patients And Methods: This is a descriptive retrospective study assessing the outcomes of CFE with profundoplasty. All patients with chronic limb-threatening ischaemia (CLTI) who attended and underwent CFE with profundoplasty with or without iliac intervention at Glan Clwyd Hospital (Wales, United Kingdom) were studied.

Exosome-mediated Transfer of lncRNA in Liver Associated Diseases; Uncovered Truths.

Exosomes are extracellular vesicles with a diameter ranging from 40 to 160 nm. They are produced by hepatocytes, cholangiocytes, hepatic stellate cells (HSCs), liver sinusoidal endothelial cells (LSECs) and Kupffer cells in liver tissue. The secretion of exosomes might vary in quantity and composition in reaction to multiple triggers and various stages of disease.

Acinetobacter baumannii clinical isolates from outbreaks in Erbil hospitals after the COVID-19 pandemic.

Introduction: Acinetobacter baumannii is endemic in hospital environments, and since the coronavirus disease 2019 (COVID-19) pandemic, multidrug-resistant A. baumannii has become more potent. This potential evolution is driven by the undetectable numbers of gene resistances it has acquired.

Innovations in Gritti-Stokes Amputation: A Focused Analysis of Immobile Patient Outcomes.

Background Major lower limb amputation is a surgical operation performed for different reasons, including life-threatening infection, ischemia, trauma, and tumors. This study aims to investigate the viability of Gritti-Stokes amputation as a suitable alternative for individuals with impaired mobility and peripheral vascular disease. Patients and methods This was a descriptive, retrospective, and observational study.