Predictive factors of endometriosis progression into ovarian cancer.

Background: In recent years, the endometriosis has overcome a noteworthy renaissance in the recognition of its potential. In certain patients, a demonstrable malignant progression of ectopic foci leading to development of ovarian cancer is seen. The knowledge of endometriosis overthrow background into endometriosis associated ovarian cancer is of paramount importance for selection of patients at risk.

The effect of essentiale on histones and nucleic acids in liver and blood-forming tissues of rats irradiated with gamma-rays.

In this paper, the influence of the hepatoprotective drug Essentiale on the target (normal and regenerating liver) and the non-target (spleen and bone marrow) rat tissues was studied after whole body irradiation with the dose of 5.7 Gy gamma-radiation. The application of the drug 24 h before irradiation alleviated all the radiation induced changes of the histones and nucleic acids in the normal and regenerating liver tissue.

Protective and therapeutic effect of silymarin on the development of latent liver damage.

Radioprotective and therapeutical effect of silymarin (Flavobion) on development and repair of latent injury in rat liver was examined by its application during the continual gamma irradiation (dose rates 0.2 and 0.6 Gy/day) or after acute gamma irradiation (dose 6 Gy).

Modification of postradiative changes of nucleic acids by the bacterial extract broncho-vaxom in rat tissues.

We have studied the influence of immunomodulator Broncho-Vaxom on the concentration and the total content of RNA and DNA in the bone marrow, spleen and regenerating liver (after partial hepatectomy) in rats irradiated with doses of 3 Gy, 6 Gy or 9 Gy of gamma radiation. Animals in all groups were partially hepatectomized (2/3 of liver mass removed) within 30 min or on the 6th and 13th day after irradiation and they were examined 30 h after resection, i.e.

Therapeutical effect of silymarin on nucleic acids in the various organs of rats after radiation injury.

The therapeutical effect of the hepatoprotective drug silymarin (Flavobion) was investigated in rats after total body gamma irradiation with a dose of 6 Gy. Silymarin (70 mg kg-1 p.o.