Publications by authors named "H Hakan Alp"

Article Synopsis
  • The study aimed to evaluate how vitamin D and memantine influence recovery in juvenile rats following repetitive brain injuries (rTBI) and to explore the mechanisms behind these effects.
  • Juvenile rats were divided into seven groups receiving different treatments, including sham surgery, trauma alone, and various combinations of memantine and vitamin D before or after trauma, with analyses conducted on brain tissues and blood samples to assess injury markers.
  • Results showed that trauma increased injury markers, but combination treatments using both vitamin D and memantine yielded the most significant therapeutic effects, particularly in group receiving both supplements before and after the injury.
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Article Synopsis
  • * Results indicated that certain tests, particularly cardiac biomarkers, blood gases, and specific drug levels, were perceived to pose a higher risk for patient harm due to erroneous results.
  • * There was strong agreement (91%) between medical biochemists and clinicians regarding the severity scores, highlighting the tests that require focused quality improvement efforts.
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Background: Acute rheumatic fever is an immunologically delayed autoimmune sequel of throat infection caused by group A streptococcus. The aim of this study was to evaluate endocan levels in patients with acute rheumatic fever and compare with the control group.

Aim: The aim of this study was to evaluate endocan levels in patients with acute rheumatic fever and compare with the control group.

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  • The study compared the effects of thymoquinone (TQ), St. John wort (SJW), and silver sulfadiazine (AgSD) on wound healing in rats subjected to burns.
  • Topical TQ significantly accelerated healing, enhanced granulation and vascularization, and improved antioxidant levels, while SJW showed some positive effects but was less effective in systemic application.
  • AgSD reduced oxidative stress but negatively impacted the wound healing process, suggesting that TQ is the most effective treatment, SJW works better topically, and AgSD should be used with caution.
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Aim: The objective was to evaluate the serum levels of neutrophil gelatinase-associated lipocalin (NGAL), hypoxia-induced factor-1 alpha (HIF-1α), and apelin 13 in patients with acute pulmonary thromboembolism (PE) and to investigate their diagnostic and prognostic role in PE patients with different mortality risk groups.

Material And Methods: This study was conducted in a tertiary referral center and included 124 subjects with 94 cases of PE and 30 cases of healthy control group. All subjects were 18 years of age or older.

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