Publications by authors named "H Hajimehdipoor"

Ferulago angulata is a medicinal herb from the Apiaceae family known for its antioxidant, anti-apoptotic, and neuroprotective properties. This study aimed to assess the effects of F. angulata extract on neurobehavioral and biochemical parameters in scopolamine-induced amnesic rats.

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Background: Fatigue is one of the most prevalent symptoms, increasing worldwide with no specific medication for fatigue. Iranian traditional medicine (ITM), or Persian medicine, is a reliable source for discovering natural medicine for diseases and their symptoms. L.

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Introduction: Alzheimer's disease (AD) is an age-dependent neurodegenerative disease. Beta-amyloid (Aβ)-induced neurotoxicity has a pivotal role in AD pathogenesis; therefore, the modulation of Aβ toxicity is the promising therapeutic approach to control the disease progression. Medicinal plants because of their multiple active ingredients are effective in complex diseases, such as AD.

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Article Synopsis
  • - This study investigates the effects of rutin, a compound studied for its anti-cancer properties, on breast cancer cell lines MDA-MB-231 and MCF-7, finding that it significantly stimulates cell proliferation compared to control groups.
  • - Rutin was shown to enhance cell migration, as evidenced by wound scratch assays, and affects the expression of important genes and proteins related to cancer progression and angiogenesis.
  • - Overall, the research suggests that rutin could promote breast cancer characteristics, indicating it may act as a phytoestrogen that stimulates invasion and migration through the epithelial-mesenchymal transition (EMT) process.
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Metastasis is a multi-step phenomenon during cancer development leading to the propagation of cancer cells to distant organ(s). According to estimations, metastasis results in over 90% of cancer-associated death around the globe. Long non-coding RNAs (LncRNAs) are a group of regulatory RNA molecules more than 200 base pairs in length.

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