Effective optical and treatment zone analysis by means of cross-over differences after lenticule extraction.

Purpose: To determine the size of the effective optical and treatment zones after lenticule extraction procedures.

Design: Retrospective case series.

Methods: A fully automated method to determine the boundaries of the optical and treatment zones of a lenticule of tissue extracted from a cornea has been developed, in which the boundaries of the corrected area are derived from differences between post and preoperative maps of several corneal metrics by determining the smallest cross-over point along each semi-meridian.

Black Phosphorus Nanoflakes: An Emerging Nanomaterial for Clinical Wound Management and Biomedical Applications.

Black phosphorus (BP), a two-dimensional material, has gathered significant attention over the last decade, primarily due to its unique physiochemical properties and potential role in various biomedical applications. This review provides an in-depth overview of the synthesis, nanomaterial properties, interactions, and biomedical uses of BP, with a particular focus on wound management. The structure, synthesis methods, and stability of BP are discussed, highlighting the high degree of nanomaterial biocompatibility and cytotoxicity.

The Acid-Buffered Engineered Gel Promotes In Vitro Cutaneous Healing and Fights Resistant Bacteria in Wounds.

: Treatment of cutaneous wound infections is becoming a major clinical challenge due to the growing problem of antimicrobial resistance associated with existing wound treatments. Two prevalent pathogens in wound infections, () and (), continue to present a serious challenge, underscoring the critical need for new therapeutic alternatives. : Novel alginate acid-buffered gels (ABF-1, ABF-2, and ABF-3) were developed using a combination of organic acids in various concentrations and buffered at a pH of 4.

Deferiprone and Gallium-Protoporphyrin Chitogel as an antimicrobial treatment: Preclinical studies demonstrating antimicrobial activity for S. aureus infected cutaneous wounds.

Staphylococcus aureus (S. aureus) is one of the most common wound pathogens with increased resistance towards currently available antimicrobials. S.