Angiogenesis-promoting effect of SKP-SC-EVs-derived miRNA-30a-5p in peripheral nerve regeneration by targeting LIF and ANGPT2.

Ischemia and hypoxia caused by vascular injury intensify nerve damage. Skin precursor-derived Schwann cells have demonstrated an accelerated in vivo pre-vascularization of tissue-engineered nerves. Furthermore, extracellular vesicles from skin precursor-derived Schwann cells (SKP-SC-EVs) show the potential in aiding peripheral nerve regeneration.

BMP2 is required for granulosa cell proliferation and primordial follicle activation in chicken.

During ovary development, the dormant primordial follicles (PF) are stimulated and begin to develop into primary follicles (PrF), a process called follicle activation. Only activated follicles can continue to grow and release the eggs in the future, making the female animal fertile. The molecular events during PF activation are not fully understood.

Fractional order system identification using a joint multi-innovation fractional gradient descent algorithm.

This paper proposes a joint multi-innovation fractional gradient descent identification algorithm for fractional order systems. First, the flexibility of fractional calculus is leveraged to design a joint fractional gradient descent algorithm capable of estimating system parameters and unknown orders. The estimated system parameters are used as the initial conditions to identify the unknown order, and the identified order is used as the update conditions for the system parameters.

Iron Deficiency Promotes Intra-leaflet Haemorrhage-induced Aortic Valve Calcification: an Experimental Study.

Background: Interleaflet haemorrhage (IH) plays a well-recognized detrimental role in calcified aortic valve disease (CAVD). However, IH-induced fibro-osteogenic responses in valvular interstitial cells (VICs) appear to be triggered under specific pathological conditions. Iron deficiency (ID), a common co-morbidity in CAVD, may influence these responses.

Robotic vs. laparoscopic gastrectomy for patients with locally advanced gastric cancer: a meta-analysis of randomized controlled trials and propensity-score-matched studies.

Background: The role of robotic surgery for the treatment of locally advanced gastric cancer remains controversial. This meta-analysis aimed to compare the short-term outcomes between robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for patients with locally advanced gastric cancer using data collected from randomized controlled trials (RCTs) and propensity score-matched (PSM) studies.

Materials And Methods: We searched PubMed, Cochrane Library, Embase, and Web of Science databases for RCTs and PSM studies comparing RG and LG.