Analysis of Changes in Viral Load and Inflammatory Cytokines, as Well as the Occurrence of Secondary Infections, in SFTS Patients Treated with Specific Treatments: A Prospective Multicenter Cohort Study.

Severe fever with thrombocytopenia syndrome (SFTS) is an acute febrile illness caused by the SFTS virus (SFTSV). We conducted this study to propose a scientific evidence-based treatment that can improve prognosis through changes in viral load and inflammatory cytokines according to the specific treatment of SFTS patients. This prospective and observational study was conducted at 14 tertiary referral hospitals, which are located in SFTS endemic areas in Korea, from 1 May 2018 to 31 October 2020.

Point Cloud Wall Projection for Realistic Road Data Augmentation.

Several approaches have been developed to generate synthetic object points using real LiDAR point cloud data for advanced driver-assistance system (ADAS) applications. The synthetic object points generated from a scene (both the near and distant objects) are essential for several ADAS tasks. However, generating points from distant objects using sparse LiDAR data with precision is still a challenging task.

Damage Localization and Severity Assessment in Composite Structures Using Deep Learning Based on Lamb Waves.

In composite structures, the precise identification and localization of damage is necessary to preserve structural integrity in applications across such fields as aeronautical, civil, and mechanical engineering. This study presents a deep learning (DL)-assisted framework for simultaneous damage localization and severity assessment in composite structures using Lamb waves (LWs). Previous studies have often focused on either damage detection or localization in composite structures.

Exploring Technology Acceptance of Healthcare Devices: The Moderating Role of Device Type and Generation.

The increasing adoption of healthcare devices necessitates a deeper understanding of the factors that influence user acceptance in this rapidly evolving area. Therefore, this study examined the factors influencing the technology acceptance of healthcare devices, focusing on radar sensors and wearable devices. A total of 1158 valid responses were used to test hypotheses, mediation, and moderation effects using SmartPLS 4.

Heterotropic Activation of Cytochrome P450 3A4 by Perillyl Alcohol.

: Perillyl alcohol (POH), a monoterpene natural product derived from the essential oils of plants such as perilla (), is currently in phase I and II clinical trials as a chemotherapeutic agent. In this study, we investigated the effect of POH on cytochrome P450 (CYP) activity for evaluating POH-drug interaction potential. : The investigation was conducted using pooled human liver microsomes (HLMs), recombinant CYP3A4 (rCYP3A4) enzymes, and human pluripotent stem cell-derived hepatic organoids (hHOs) employing liquid chromatography-tandem mass spectrometry.