Acute tubular necrosis after inhalation exposure to methylene chloride. Report of a case.

Nephrotoxic reaction occurred after inhalation exposure to methylene chloride. This exposure is associated with acute renal failure, myoglobinuria, hypocomplementemia, and liver enzyme elevations. Pathologic specimens, both light and electron microscopic, demonstrate renal tubular damage.

An argument for the attendance of clinicians at autopsy.

We recorded the attendance of clinicians at the autopsies they had requested, and following personal notification that the autopsy was in progress. Of 679 residents paged , 37% attended and 63% did not. Of 786 internists paged , 36% attended and 64% did not.

Autopsies in a modern teaching hospital. A review of 2,537 cases.

We reviewed the clinical charts and the postmortem findings of 2,537 autopsies, and correlated them by constructing a "concordance score." In 2,293 cases (90%), the primary disease, as diagnosed at autopsy, had been recognized as such clinically, but in 244 cases (10%) it had not. In 2,300 cases a second disease was present, which had been diagnosed clinically in 1,795 patients.