Publications by authors named "H H Altalib"
Background And Objectives: The most effective antiseizure medications (ASMs) for poststroke seizures (PSSs) remain unclear. We aimed to determine outcomes associated with ASMs in people with PSS.
Methods: We systematically searched electronic databases for studies on patients with PSS on ASMs.
Objective: To investigate phenotypes of comorbidity before and after an epilepsy diagnosis in a national cohort of post-9/11 Service Members and Veterans and explore phenotypic associations with mortality.
Methods: Among a longitudinal cohort of Service Members and Veterans receiving care in the Veterans Health Administration (VHA) from 2002 to 2018, annual diagnoses for 26 conditions associated with epilepsy were collected over 5 years, ranging from 2 years prior to 2 years after the year of first epilepsy diagnosis. Latent class analysis (LCA) was used to identify probabilistic comorbidity phenotypes with distinct health trajectories.
Article Synopsis
- The study investigates the relationship between the timing of traumatic brain injury (TBI) and mortality in veterans with epilepsy, finding that TBI increases mortality risk, especially when it occurs shortly after epilepsy onset.
- Among almost 1 million veterans, those with epilepsy had a significantly higher mortality rate compared to controls, with the most severe risk observed in those with TBI within 6 months of epilepsy diagnosis.
- Results indicate that the timing of TBI in relation to epilepsy is crucial, highlighting a need for targeted care for veterans experiencing these conditions.
Patients with epilepsy often present with concurrent psychiatric disorders, posing unique challenges for healthcare providers. This review explores the intricate relationship between psychiatric comorbidities, epilepsy, and psychotropic medications to inform clinical decision-making. The bidirectional association between epilepsy and psychiatric conditions complicates treatment, with psychiatric symptoms preceding or following seizure onset.
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