Publications by authors named "H Grand"

Background: Group A Streptococcus is responsible for severe and potentially lethal invasive conditions requiring intensive care unit (ICU) admission, such as streptococcal toxic shock-like syndrome (STSS). A rebound of invasive group A streptococcal (iGAS) infection after COVID-19-associated barrier measures has been observed in children. Several intensivists of French adult ICUs have reported similar bedside impressions without objective data.

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Importance: Keeping a diary for patients while they are in the intensive care unit (ICU) might reduce their posttraumatic stress disorder (PTSD) symptoms.

Objectives: To assess the effect of an ICU diary on the psychological consequences of an ICU hospitalization.

Design, Setting, And Participants: Assessor-blinded, multicenter, randomized clinical trial in 35 French ICUs from October 2015 to January 2017, with follow-up until July 2017.

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Background: Post-intensive care syndrome includes the multiple consequences of an intensive care unit (ICU) stay for patients and families. It has become a new challenge for intensivists. Prevention programs have been disappointing, except for ICU diaries, which report the patient's story in the ICU.

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Article Synopsis
  • Septic shock, often complicated by acute kidney injury (AKI), is a major cause of death in critically ill patients, prompting the investigation of high-volume haemofiltration (HVHF) as a potential treatment.
  • The study was a clinical trial involving 140 patients with septic shock and AKI, comparing the effects of HVHF and standard-volume haemofiltration (SVHF) on 28-day mortality over a 96-hour period.
  • Results showed no significant difference in mortality rates between the HVHF group (37.9%) and the SVHF group (40.8%), leading to the conclusion that HVHF does not improve outcomes in these patients and is not recommended for treatment.
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