Publications by authors named "H Goris"

The use of saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sparks debate due to presumed lower sensitivity and lack of standardization. Our aim was to evaluate the performance characteristics of (i) saliva collected by the ORAcollect device as a matrix for SARS-CoV-2 reverse-transcriptase polymerase chain reaction (RT-PCR), and (ii) 2 saliva rapid antigen tests (AgRDT). From 342 ambulatory individuals, both a nasopharyngeal swab and saliva sample via ORAcollect were obtained for a SARS-CoV-2 RT-PCR test.

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Article Synopsis
  • SARS-CoV-2 can be transmitted from humans to animals, which may create new reservoirs and develop variants that could lead to future human outbreaks.
  • During a study in Antwerp, researchers tested Norway rats from the sewer system for SARS-CoV-2 after a COVID-19 peak, focusing on detecting the virus and antibodies.
  • All 39 tissue samples tested negative for the virus, and while three rat serum samples appeared positive for antibodies, they did not neutralize the virus, indicating no infection; yet, ongoing monitoring is recommended due to potential new variants.
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Background: European Society of Cardiology guidelines for the treatment of heart failure (HF) prescribe uptitration of angiotensin-converting enzyme inhibitors (ACE-I) and β-blockers to the maximum-tolerated, evidence-based dose. Although HF prognosis can drastically improve when correctly implementing these guidelines, studies have shown that they are insufficiently implemented in clinical practice.

Objective: The aim of this study was to verify whether supplementing the usual care with the CardioCoach follow-up tool is feasible and safe, and whether the tool is more efficient in implementing the guideline recommendations for β-blocker and ACE-I.

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