Protirelin (thyrotropin-releasing hormone) in thyroid gland: possible involvement in regulation of thyroid status.

Aim: To establish the presence of the hypothalamic hormone protirelin (thyrotropin-releasing hormone, TRH) in human thyroid and to investigate whether the concentration of this peptide in the thyroid gland is sensitive to thyroid status.

Methods: A procedure has been developed for the determination of TRH in the thyroid gland, distinct from TRH-like peptides which also react with TRH-antibody.

Results: Human thyroid was shown to contain both authentic TRH and TRH-like peptides, a similar pattern was seen in a range of animal thyroids.

[Problems of medical documentation in the hospital].

Problems of medical documentation arise from an explosive increase of data-volumes, complexity and multiplicity in data-management. The causality of that development, the possibility of computerized support in repetitive data-management, the economic, organizing and scientific problems are widely discussed. Solving the problems in the hospital a potent middle-ranged computer offers his services under certain circumstances.