Publications by authors named "H Gewirtz"
Article Synopsis
- Angina and dyspnea in patients with normal coronary arteries present a diagnostic challenge, with many possibly suffering from coronary microvascular dysfunction (CMD) rather than traditional coronary artery disease.
- Positron emission tomography (PET) is used to measure myocardial blood flow (MBF) and reserve (MFR), which helps noninvasively detect CMD, leading to better understanding of patients' symptoms.
- A consensus document is in development to standardize the diagnosis and reporting for CMD to improve treatment decisions and patient outcomes, involving experts from around the world.
Article Synopsis
- - Factors causing "fixed" defects in myocardial perfusion imaging (MPI) SPECT are discussed, highlighting both technical and physiological reasons.
- - The lack of absolute quantitative measurement of myocardial blood flow (MBF) in traditional SPECT imaging complicates the assessment of defect changes during stress testing.
- - Cardiac PET MPI offers absolute MBF measurements, which can enhance clinical understanding of fixed defects and aid in identifying multi-vessel coronary artery disease (CAD), especially with the potential widespread use of 18F flurpiridaz.
Chronic kidney disease (CKD), defined as dysfunction of the glomerular filtration apparatus, is an independent risk factor for the development of coronary artery disease (CAD). Patients with CKD are at a substantially higher risk of cardiovascular mortality compared with the age- and sex-adjusted general population with normal kidney function. The risk of CAD and mortality in patients with CKD is correlated with the degree of renal dysfunction including presence of microalbuminuria.
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