Bone remodelling around the Metha short stem implant - Clinical and dual-energy x-ray absorptiometry (DXA) results.

Objective: Bony ingrowth of short stems is under investigation.

Method: Over one year bony reactions around the Metha stem were investigated using the DXA method in a standardized zonal system (19 ROIs). Clinical results were documented using the HHS.

Comparable short-term results seen with standard and high-flexion knee arthroplasty designs in European patients.

Purpose: In a prospective study we evaluated outcomes of total knee arthroplasty (TKA) procedures in 62 patients with a follow up of 12 months to test our hypothesis that high-flexion CR (cruciate retaining) TKA provides a better range of motion and better outcome than standard CR design in Central European patients with their special problems and demands.

Methods: Patients were randomly divided into two groups (high flex vs. standard).

Establishment of a new methicillin resistant Staphylococcus aureus animal model of osteomyelitis.

Purpose: The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections is currently a major health care problem. Vancomycin is still often the first-line anti-microbiological agent for treating such infections; however, a recent decline in efficacy of vancomycin in MRSA infections has raised concerns and accelerated the search for new antibiotics. The aim of this study was to establish a MRSA peri-implant osteomyelitis animal model for future testing of new anti-microbiological agents under typical MRSA infection conditions.

Core decompression combined with implantation of a demineralised bone matrix for non-traumatic osteonecrosis of the femoral head.

Introduction: Core decompression is the standard surgical procedure in the treatment of early stage non-traumatic osteonecrosis of the femoral head (ONFH). However, there is still a debate whether decompression in combination with supplementary augmentation by bone grafts, growth factors, or cell implementation is superior to conventional decompression alone. This study evaluated patients after core decompression combined with an augmentation by a demineralised bone matrix, and particularly aimed to report long-term conversion rates to total hip replacement (THR).

Implant stability in the treatment of MRSA bone implant infections with linezolid versus vancomycin in a rabbit model.

The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) infections represents a significant healthcare burden. Vancomycin and linezolid exhibit potent clinical and microbiological activity in MRSA infections. Our purpose was to investigate the efficacy of linezolid versus vancomycin in experimental implant infections and the influence on implant stability in a rabbit model.