Publications by authors named "H G Morales"
Acute Infusion-Related Side Effects of Amphotericin B Lipid Complex (ABLC) in Oncohematological Patients: Real-World Data from Brazilian Reference Centers.
Infect Dis Ther
November 2024
Introduction: Amphotericin B lipid complex (ABLC) is an effective antifungal agent for treating invasive fungal infections (IFIs) even though its formulation is associated with potential adverse events, including those related to its infusion. This study aimed to analyze the incidence of acute infusion-related side effects (IRSE) associated with ABLC and their relationship with the profile of patients with oncohematological disease admitted in Brazilian reference tertiary hospitals.
Methods: This is an observational retrospective study that included clinical records of patients hospitalized, in a period of 6 years, diagnosed with probable or proved IFI and treated with at least two doses of ABLC.
Fowl typhoid (FT) caused by Gallinarum (SG) is a poultry disease distributed worldwide that has been eradicated in commercial production of many developed countries but still persists in many developing countries. Vaccination is one of the main strategies to reduce mortality, clinical signs, and vertical or horizontal transmission. The aim of this work was to assess the protection against FT conferred by vaccines based on Enteritidis (SE), SG, or a combination.
View Article and Find Full Text PDFWe present a genome assembly from an individual male , formerly (the Mauritius Parakeet; Chordata; Aves; Psittaciformes; Psittacidae). The genome sequence is 1203.8 megabases in span.
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- The study of kākāpō genomic data reveals insights into the past ecology and evolution of this endangered parrot species.
- Researchers investigated the feather color polymorphism in kākāpō, finding a balanced presence of green and olive colors despite a small population size of less than 250 birds.
- It is suggested that the color variation was maintained through balancing selection influenced by an extinct apex predator, representing an evolutionary legacy from a much larger ancestral population.
Maintaining a diverse gene pool is important in the captive management of zoo populations, especially in endangered species such as the pink pigeon (Nesoenas mayeri). However, due to the limited number of breeding individuals and relaxed natural selection, the loss of variation and accumulation of harmful variants is inevitable. Inbreeding results in a loss of fitness (i.
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