Phytoplasma-Associated Diseases in South America: Thirty Years of Research.

Phytoplasma-associated diseases are mainly insect-transmitted and are present worldwide. Considering that disease detection is a relevant environmental factor that may elucidate the presence of these diseases, a review reporting the geographic distribution of phytoplasma taxa in geographically consistent areas helps manage diseases appropriately and reduce their spreading. This work summarizes the data available about the identification of the phytoplasma associated with several diverse diseases in South America in the last decades.

TgTKL4 Is a Novel Kinase That Plays an Important Role in Morphology and Fitness.

Protein kinases of the protozoan parasite Toxoplasma gondii have been shown to play key roles in regulating parasite motility, invasion, replication, egress and survival within the host. The tyrosine kinase-like (TKL) kinase family of proteins are a set of poorly studied kinases that our recent studies have indicated play a critical role in biology. In this study, we focused on TgTKL4, another member of the TKL family that is predicted to confer parasite fitness.

Outcome and owner assessment after single-session bilateral tibial plateau leveling osteotomy in 127 dogs.

Objective: To retrospectively evaluate complication rates following bilateral tibial plateau leveling osteotomy (TPLO) as well as owner assessment of outcomes and post-operative management.

Methods: Medical records of dogs presenting with bilateral cranial cruciate ligament (CCL) disease that underwent single-session bilateral TPLO from 2015 to 2019 in 1 referral practice were retrospectively reviewed. A non-validated questionnaire was sent to the owners to assess their ability to cope during the rehabilitation period, as well as procedure outcome.

Revision of the ' Phytoplasma' species description guidelines.

The genus ' Phytoplasma' was proposed to accommodate cell wall-less bacteria that are molecularly and biochemically incompletely characterized, and colonize plant phloem and insect vector tissues. This provisional classification is highly relevant due to its application in epidemiological and ecological studies, mainly aimed at keeping the severe phytoplasma plant diseases under control worldwide. Given the increasing discovery of molecular diversity within the genus '.

Sanfilippo syndrome type B: Analysis of patients diagnosed by the MPS Brazil Network.

Mucopolysaccharidosis type IIIB is a rare autosomal recessive disorder characterized by deficiency of the enzyme N-acetyl-alpha-d-glucosaminidase (NAGLU), caused by biallelic pathogenic variants in the NAGLU gene, which leads to storage of heparan sulfate and a series of clinical consequences which hallmark is neurodegeneration. In this study clinical, epidemiological, and biochemical data were obtained from MPS IIIB patients diagnosed from 2004-2019 by the MPS Brazil Network ("Rede MPS Brasil"), which was created with the goal to provide an easily accessible and comprehensive investigation of all MPS types. One hundred and ten MPS IIIB patients were diagnosed during this period.