Publications by authors named "H G Juncker"
Article Synopsis
- Maternal stress during the postpartum period affects the nutrient composition and microbiome of human milk (HM), potentially impacting early development and mental health outcomes for infants.
- A study involving high-stress (HS) and control groups analyzed HM microbiome changes, revealing distinct differences in bacterial composition, particularly showing HS mothers had altered levels of certain bacteria like reduced Streptococcus and increased Staphylococcus.
- The findings indicate a strong correlation between maternal stress and changes in the HM microbiome, suggesting these alterations could influence infant gut colonization and overall health, necessitating further research on their implications.
Article Synopsis
- Amino acids in human milk are crucial for infant development, and maternal lifestyle may affect their composition, but it's unclear how maternal dietary intake influences this.
- This study analyzed data from the Amsterdam Mother's Milk study involving 123 lactating women to investigate the relationship between maternal amino acid intake and their concentration in breast milk during the first month after childbirth.
- Results indicated some negative and positive associations between maternal intake and specific amino acids in milk, but these findings were less significant after adjusting for multiple tests, suggesting that protein intake may not significantly impact breast milk amino acid composition in affluent settings.
Introduction: Upon vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) humans will start to produce antibodies targeting virus specific antigens that will end up in circulation. In lactating women such antibodies will also end up in breastmilk, primarily in the form of secretory immunoglobulin A1 (SIgA1), the most abundant immunoglobulin (Ig) in human milk. Here we set out to investigate the SIgA1 clonal repertoire response to repeated SARS-CoV-2 vaccination, using a LC-MS fragment antigen-binding (Fab) clonal profiling approach.
View Article and Find Full Text PDFBackground: Maternal stress in the postpartum period affects not only the mother but also her newborn child, who is at increased risk of developing metabolic and mental disorders later in life. The mechanisms by which stress is transmitted to the infant are not yet fully understood. Human milk (HM) is a potential candidate as maternal stress affects various components of HM, e.
View Article and Find Full Text PDFBackground: Moderate exercise results in a significant increase in serum and salivary immunoglobulins. Maternal physical activity might therefore also be a factor influencing antibody levels in human milk. This study aims to determine the influence of physical activity on SARS-CoV-2-specific Immunoglobulin A (IgA) in human milk and Immunoglobulin G (IgG) in serum.
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