[The Candida infected hen's egg. An alternative test system for systemic anticandida activity].

The Candida infected, embryonated hen's egg is a realistic complement for the model of the Candida infected mouse and can be used in the search for new systemically active antimycotics. This alternative method is rapid, sensitive convincing and inexpensive. The use of the embryonated hen's egg in an anti-Candida screening can reduce the use of small laboratory animals to a considerable amount.

Sex differences in dehydroepiandrosterone metabolism in the rat: different plasma levels following ingestion of DHEA-supplemented diet and different metabolite patterns in plasma, bile and urine.

Plasma dehydroepiandrosterone (DHEA) and DHEA sulfate levels were determined by an enzyme immunoassay in male and female Sprague-Dawley rats fed a diet containing 0.6% or 0.3% DHEA.

[2-Amino-oxazoles as potential H-bonding agents in virostatic research. 4. Pharmacokinetics and pharmacologic-toxicologic profile of 2-guanidino-4,5-dipropyloxazole hydrochloride].

Out of the group of 2-amino-oxazoles 1 was found to be the most potent antiviral compound. Following p.o.