Publications by authors named "H G Falconer"
Background: In a previous phase II trial, intraperitoneal local anaesthetics shortened the time interval between surgery and adjuvant chemotherapy, an endpoint associated with improved survival in advanced ovarian cancer. Our objective was to test this in a phase III trial.
Methods: A double-blind, phase III parallel superiority trial was conducted at two university hospitals in Sweden, within a public and centralised healthcare system.
Article Synopsis
- People with T1a cervical cancer usually do well, but there's still a chance their cancer might come back, and doctors need better guidance on how to manage this.
- A study looked at over 900 patients from different hospitals to find out more about the chances of cancer returning after surgery.
- The study found that only 4.1% of patients had their cancer return, and it happened more often in certain groups, showing that certain things like lymphovascular space invasion (LVSI) can change the risk.
Article Synopsis
- In the FIGO 2018 classification, women with early-stage cervical cancer are now classified differently based on their tumor's size and spread, which could change how they are treated.
- A study looked at a group of 992 women with specific types of cervical cancer to see how often the cancer spread to lymph nodes (pN+) and found that certain factors like lymphovascular space invasion (LVSI) increased the risk of spread.
- The results suggest that women with LVSI-positive tumors should have lymph node checks, but those with LVSI-negative tumors may not need this if their tumor size and other factors are considered.
Introduction: Assessment of retroperitoneal nodes is an important part of the surgical staging of gynecologic cancers. Although pelvic and paraaortic lymphadenectomy have been widely described by different authors, there is little consensus on the description of the different surgical steps for each procedure. An Intergroup Committee on Onco-Gyn Minimally Invasive Surgery has been established with members of the European Society for Gynecological Endoscopy (ESGE), European Society of Gynaecological Oncology (ESGO) and the Society of European Robotic Gynaecological Surgery (SERGS).
View Article and Find Full Text PDFSurvival associated with the use of sentinel lymph node in addition to lymphadenectomy in early-stage cervical cancer treated with surgery alone: A sub-analysis of the Surveillance in Cervical CANcer (SCCAN) collaborative study.
Eur J Cancer
November 2024
Aim: The aim of this study was to assess whether the use of sentinel lymph node (SLN) in addition to lymphadenectomy was associated with survival benefit in patients with early-stage cervical cancer.
Methods: International, multicenter, retrospective study.
Inclusion Criteria: cervical cancer treated between 01/2007 and 12/2016 by surgery only; squamous cell carcinoma, adenocarcinoma, adenosquamous carcinoma, FIGO 2009 stage IB1-IIA2, negative surgical margins, and laparotomy approach.